cocaine addiction treatment

Cocaine DrugFacts National Institute on Drug Abuse NIDA

Research shows that when treating addictions to opioids (prescription pain relievers or drugs like heroin or fentanyl), medication should be the first line of treatment, usually combined with some form of behavioral therapy or counseling. Medications are also available to help treat addiction to alcohol and nicotine. For promoting abstinence in patients with CUD, no therapy has been shown to be more effective than VBRT, especially when VBRT is coupled with community reinforcement therapy. VBRT is based on the behavioral principle that a behavior that is rewarded is more likely to be repeated. In VBRT, patients receive vouchers redeemable for goods and services in the community contingent upon achieving a predetermined therapeutic goal, such as drug abstinence.

cocaine addiction treatment

Patients with CUD appear to fare better when they are seen several times per week compared to once a week, but IOT can provide some benefit even in relatively low–intensity treatments. To test the potential of topiramate for the treatment of CUD, our laboratory (60) carried out a pilot study involving 40 subjects with DSM-IV cocaine dependence, treated for a period of 13 weeks. Subjects were randomly assigned to topiramate (200 mg) daily or to placebo. Topiramate-treated subjects showed a significantly higher rate of abstinence during the last 5 weeks of the trial compared to placebo-treated patients.

What are the Side Effects of Cocaine Addiction?

The efficacy of modafinil may also be sensitive to degree of adherence to treatment. In most trials, modafinil has been shown to be well tolerated and it has low abuse liability, making it a potentially safer choice of dopamine agonist for the treatment of CUD. The most common treatment for CUD is a combination of group, individual, and sometimes family therapy provided in several sessions per week, known as intensive outpatient therapy (IOT).

This addiction can be difficult to treat, and the majority of those seeking treatment for cocaine addiction are polydrug users (use more than one drug recreationally). Withdrawal from different categories of drugs — such as depressants, stimulants or opioids — produces different side effects and requires different approaches. Detox may involve gradually reducing the dose of the drug or temporarily substituting other substances, such as methadone, buprenorphine, or a combination of buprenorphine and naloxone.

Common medications used to treat drug addiction and withdrawal

Behavioral therapy is also available to help treat underlying causes of addiction, alongside any mental health issues of the patient. Agonist treatments have been used successfully to treat both opioid and tobacco use disorders (25–27). Ideally, in agonist treatment, the medication chosen should be one that activates the same receptor as the abused drug, thus exerting similar effects but with pharmacological properties that render it less abusable than the abused drug. Generally, drugs that enter the brain more slowly, have longer duration of action, or are partial agonists rather than full agonists tend to have less addictive potential. These drugs may be effective treatment for several forms of substance use disorder. Both methadone, because of its slow onset of action, and buprenorphine, by virtue of its partial agonist activity at the opioid receptors, are effective agonist treatments for opioid use disorder.

Additionally, medications are used to help people detoxify from drugs, although detoxification is not the same as treatment and is not sufficient to help a person recover. Detoxification alone without subsequent treatment generally leads to resumption of drug use. While relapse is a normal part of recovery, for some drugs, it can be very dangerous—even deadly. If a person uses as much of the drug as they did before quitting, they can easily overdose because their bodies are no longer adapted to their previous level of drug exposure.

Cholinergic medications

Although only 32% of the subjects completed the trial, the retention rate was equally poor in both medicated and control groups. Because this was a proof-of-concept trial, the investigators applied stringent retention criteria, requiring participants to provide at least 75% of the requested data for any 2-week period of the trial. Therefore, failing to attend two visits in a given week would, in most cases, result in the subject being discontinued from the study (32). Because no medications have been approved for the treatment of CUD, psychosocial treatment is currently the standard treatment.

  • First, in an open pilot trial,15 propranolol was shown to be safe and well tolerated by cocaine-dependent patients.
  • “The deaths that are included in this study, when we say a death involves fentanyl and cocaine, that means that at some point a medical examiner or coroner determined that both were important factors in causing death,” Shover said.

For anyone considering treatment for Cocaine addiction, it’s helpful to seek a substance abuse evaluation from an addiction professional to determine the right type of support. This determination is based on a number of factors including the severity of the addiction, living environment, and psychiatric and medical needs. Cocaine is a dangerous and addictive drug, but with proper treatment, recovery is possible.

If the drug is discontinued, withdrawal symptoms, with physical effects, can occur. A strong craving for cocaine is the most prominent effect of withdrawal, but other symptoms usually occur as well. Cocaine addiction accounts for roughly 6% of all drug rehab admissions in the United States.

cocaine addiction treatment

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